Sculptra®

Sculptra® Aesthetic is an FDA-approved facial injectable treatment on the market that helps
boost the skin’s own natural collagen production to restore its inner structure. It also provides long-lasting results — more than two years.

Sculptra® Aesthetic is different from hyaluronic acid fillers because it helps treat an underlying cause of facial volume loss —the reduction of collagen.

Collagen acts as the skin’s support structure and helps maintain skin’s shape. As we age, we lose collagen, and the skin’s inner structure is weakened, reducing its ability to maintain elasticity and moisture.

Sculptra® Aesthetic works deep within the skin’s surface and is gradually and naturally absorbed by the body to help stimulate collagen production, reinforcing the skin’s inner structure.

Sculptra® Aesthetic is a key to unlocking a more youthful-looking appearance because it helps restore facial volume and improve the look of the nasolabial folds (smile lines), marionette lines, pre-auricular wrinkles (the vertical wrinkles in front of the ears), radial cheek folds (vertical wrinkles on the lower cheek) and chin wrinkles.

On average, three treatments sessions are needed over a few months. The treatments are
scheduled at least 3 weeks apart so the results are subtle and develop gradually over time.

Sculptra® Aesthetic is made from Poly-L-lactic acid (PLLA) and has been on the market for 10 years in the U.S. and 20 years in Europe.

Side effects of Sculptra® Aesthetic treatment are generally mild to moderate in severity and
similar to those seen with hyaluronic acid dermal fillers and may include injection site swelling, tenderness, redness, pain, bruising, bleeding, itching and lumps. In the Sculptra® Aesthetic clinical study, most side effects resolved in 7 days or less.



Important Safety Information
Indication: Sculptra® Aesthetic (injectable poly-L-lactic acid) is indicated for use in people with healthy immune systems as a single regimen for the correction of shallow to deep nasolabial fold contour deficiencies and other facial wrinkles in which deep dermal grid pattern (cross-hatch) injection technique is appropriate.
Sculptra® Aesthetic should not be used by people that are allergic to any ingredient of the product or have a history of keloid formation or hypertrophic scarring. Safety has not been established in patients who are pregnant, lactating, breastfeeding, or under 18 years of age. Sculptra® Aesthetic has unique injection requirements and should only be used by a trained physician. Contour deficiencies should not be overcorrected because they are expected to gradually improve after treatment. Sculptra® Aesthetic should not be injected into the blood vessels as it may cause vascular occlusion, infarction or embolic phenomena. Use at the site of skin sores, cysts, pimples, rashes, hives or infection should be postponed until healing is complete. Sculptra® Aesthetic should not be injected into the red area (vermillion) of the lip or in the peri-orbital area. The most common side effects after initial treatment include injection site swelling, tenderness, redness, pain, bruising, bleeding, itching and lumps. Other side effects may include small lumps under the skin that are sometimes noticeable when pressing on the treated area. Larger lumps, some with delayed onset with or without inflammation or skin discoloration, have also been reported. Sculptra® Aesthetic is available only through a licensed practitioner. View the complete instructions for use at http://www.SculptraAesthetic.com

1Stein P, Vitavska O, Kind P, Hoppe W, Wieczorek H, Schürer NY. The biological basis for poly-L-lactic acid-induced augmentation. J Dermatol Sci. 2015;78:26-33.
2Goldberg D, Guana A, Volk A, Daro-Kaftan E. Single-arm study for the characterization of human tissue response to injectable poly-L-lactic acid. Dermatol Surg. 2013;39:915-922.
3 Sculptra® Aesthetic injectable poly-L-lactic acid. Instructions for Use. Fort Worth, TX: Galderma Laboratories, L.P., 2016.
4Brown SA, Rohrich RJ, Baumann L, et al. Subject global evaluation and subject satisfaction using injectable poly-Llactic acid versus human collagen for the correction of nasolabial fold wrinkles. Plast Reconstr Surg.
5Quan T, Wang F, Shao Y, et al. Enhancing structural support of the dermalmicroenvironment activates fibroblasts, endothelial cells, and keratinocytes in aged human skin in vivo. J Invest Dermatol. 2013 Mar;133(3):658-667.
6Ganjoo A. Aging skin. In: Venkataram M, ed. ACS(I) Textbook on Cutaneous and Aesthetic Surgery. 1st ed. New Delhi, India: Jaypee Brothers Medical Publishers; 2012:545-549.
7 Vleggaar D, Fitzgerald R. Dermatological implications of skeletal aging: a focus on supraperiosteal voluminization for perioral rejuvenation. J Drugs Dermatol. 2008;7(3):209-220. 2011;127(4):1684-1692.
8Dermal Fillers Approved by the Center for Devices and Radiological Health. Accessed April 25 2018. Available at: https://www.fda.gov/medicaldevices/productsandmedicalprocedures/cosmeticdevices/wrinklefillers/ucm227749.
htm#approved
9 Lam SM, Azizzadeh B, Graivier M. Injectable poly-L-lactic acid (Sculptra): technical considerations in soft tissue contouring. Plast Reconstr Surg. 2006 Sep;118(3 Suppl):55S-63S.
© 2019 Galderma Laboratories, L.P. All trademarks are the property of their respective owners. USMP/SCA/0024/0418(1)
<span>%d</span> bloggers like this: